反应详情

A mixture containing 138.5 grams (0.522 mole) of 2,6-dichloro-4-(trichloromethyl)pyridine and 34 grams (0.187 mole) of Antimony trifluoride was heated to 80°-84° C. and maintained under agitation for 23 minutes. During this step, a slow stream of chlorine gas was passed over the surface of the reaction mixture. The reaction mixture was steam distilled and the crude 2,6- dichloro-4-(dichlorofluoromethyl)pyridine product was purified by fractionation. The product had a boiling point of 74°-76° C. at 1.0 millimeter of mercury.

1. temperaturewas heated to 80°-84° C.
2. temperaturemaintained under agitation for 23 minutes
3. distillationdistilled
4. customthe crude 2,6- dichloro-4-(dichlorofluoromethyl)pyridine product was purified by fractionation