HuagongsheHuagongshe Chemistry Print Report · For research reference only
Magnesium peroxide (Mg(O2)) → 2-Chloro-3-methylbenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Magnesium peroxide (Mg(O2)) | HCID 61745 | — |
| Reactant | 2-Chloro-3-methylbenzoic acid | HCID 139879 | — |
| Reactant | Diboron | HCID 6328200 | — |
| Reactant | (2-Chloro-3-methylphenyl)methanol | HCID 14534589 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Chloro-3-methylbenzaldehyde | HCID 14492779 | — |
Reaction Steps
2-Chloro-3-methylbenzoic acid was reduced by treating with diborane in tetrahydrofuran and the resulting 2-chloro-3-methylbenzyl alcohol was oxidized with activated magnesium dioxide in methylene chloride to give 2-chloro-3-methylbenzaldehyde.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04062961 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-e128f60000ba484d87be01489aa5d34b |
| Source note | uspto-grants-1977_12 |