HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21393798, compound → 8-Amino-7-chloro-1,2,3,4-tetrahydroisoquinoline hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21393798 | HCID 21393798 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 8-Amino-7-chloro-1,2,3,4-tetrahydroisoquinoline hydrochloride | HCID 21393827 | — |
Reaction Steps
Platinum oxide (0.1 g.) in methanol is reduced with hydrogen at atmospheric pressure. 8-Acetamido-7-chloroisoquinoline hydrochloride (1.0 g.) is treated as in Example 11 to give 8-amino-7-chloro-1,2,3,4-tetrahydroisoquinoline hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04062961 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-bc88bf3fc3914607a326a7b4b99f680f |
| Source note | uspto-grants-1977_12 |