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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 461496Generated: October 30, 2026

7-Nitro-8-trifluoromethylisoquinoline → HCID 20523201, compound

https://huagongshe.com/reaction/461496

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Nitro-8-trifluoromethylisoquinolineHCID 21393838—
CatalystZincHCID 23994—
SolventAcetic AcidHCID 176—
ProductHCID 20523201HCID 20523201—

Reaction Steps

Reducing the 7-nitro group of 7-nitro-8-trifluoromethylisoquinoline with zinc and acetic acid by the procedure of Example 17 gives 7-amino-8-trifluoromethylisoquinoline. Hydrogenating by the procedure of Example 9 gives 7-amino-8-trifluoromethyl-1,2,3,4-tetrahydroisoquinoline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04062961
Source datasetuspto-grants-1977_12
ORD IDord-5fcb407c24de4618a11f63fc4cb2dcbc
Source noteuspto-grants-1977_12