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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 461498Generated: October 30, 2026

Methylamine → HCID 21393875, compound

https://huagongshe.com/reaction/461498

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
ReactantHCID 15896351HCID 15896351—
Reactant1,2,3,4-Tetrahydroisoquinolin-8-amineHCID 20523209—
ProductHCID 21393875HCID 21393875—

Reaction Steps

By the procedure of Example 15, 8-amino-1,2,3,4-tetrahydroisoquinoline is converted to 2-acetyl-8-chlorosulfonyl-1,2,3,4-tetrahydroisoquinoline. Reacting with metylamine by the procedure of Example 27 and hydrolyzing to remove the 2-acetyl group gives 8-methylsulfamoyl-1,2,3,4-tetrahydroisoquinoline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04062961
Source datasetuspto-grants-1977_12
ORD IDord-16b474c8c4814457a247798590fcaae7
Source noteuspto-grants-1977_12