4-Chlorobenzoyl chloride → HCID 20496044, compound

Participants

Reaction Steps

To a vigorously stirred solution of aluminium chloride (0.2 mole) in carbon disulphide (200 ml.) at 0° C was added a mixture of benzylacetone (0.1 mole) and p-chlorobenzoyl chloride (0.1 mole) throughout 20 minutes. After a further hour at 0° C, the reaction was allowed to reach room temperature and left overnight. The supernatant carbon disulphide was decanted off and the crude, brown residual oil, was poured carefully onto a mixture of ice and concentrated hydrochloric acid. Work-up in the usual way afforded an oil, which, after trituration with acetone and re-crystallisation from benzene/60°-80° C petrol, gave pure 4-[4-(p-chlorobenzoyl)phenyl]-2-butanone as colourless needles, m.pt. 91° - 2° C.

Provenance & Evidence