HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Aminohydantoin → alpha-[[[(2,4-Dioxo-1-imidazolidinyl)-amino]carbonyl]amino]-2-thiopheneacetic acid, ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Aminohydantoin | HCID 72823 | — |
| Reactant | alpha-Isocyanato-2-thiopheneacetic acid, ethyl ester | HCID 54068691 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | alpha-[[[(2,4-Dioxo-1-imidazolidinyl)-amino]carbonyl]amino]-2-thiopheneacetic acid, ethyl ester | HCID 86735284 | — |
Reaction Steps
By reacting 10.60 g. of DL-α-isocyanato-2-thiopheneacetic acid, ethyl ester with 5.75 g. of 1-amino-2,4-dioxoimidazolidine in 250 ml. of dioxane according to the procedure of Example 5, 15.6 g. of DL-α-[[[(2,4-dioxo-1-imidazolidinyl)-amino]carbonyl]amino]-2-thiopheneacetic acid, ethyl ester is obtained, m.p. 151°-155°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04063019 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-d8b1c81ab80b4eae9fdbc3ce052bd370 |
| Source note | uspto-grants-1977_12 |