反应详情

A mixture of 9.23 g. of 3-nitro-4-chloro-benzophenone, 10 ml. of ethanol and 10.3 g. of N-methyl-N-octylamine is stirred at 80° to 85° C for 30 minutes, and then the mixture is poured onto 100 ml. of ice water. The aqueous phase is extracted with 2x75 ml. of benzene. The benzene phases are combined, washed with distilled water with chloride-free, dried over anhydrous magnesium sulphate, filtered, and evaporated in vacuo. 11.57 g. of 3-nitro-4-(N-methyl-N-octylamino)-benzophenone are obtained in the form of an oily residue. On the basis of thin layer chromatographical examination, a pure, uniform product is obtained.

1. additionA mixture of 9.23 g
2. additionthe mixture is poured onto 100 ml
3. extractionThe aqueous phase is extracted with 2x75 ml
4. washwashed with distilled water with chloride-free
5. dry with materialdried over anhydrous magnesium sulphate
6. filtrationfiltered
7. customevaporated in vacuo