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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 461632Generated: October 25, 2026

1H-Indole-3-thiol → 3-(Indol-3-ylthio)crotonic acid

https://huagongshe.com/reaction/461632

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Indole-3-thiolHCID 10200—
Reactant2-Butynoic acidHCID 68535—
Product3-(Indol-3-ylthio)crotonic acidHCID 20326606—

Reaction Steps

By the same method as described in Example 1, 0.2 mole each of 3-mercaptoindole and tetrolic acid gives 10.2 g of product after recrystallization from acetonitrile, mp 201°-202° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04064123
Source datasetuspto-grants-1977_12
ORD IDord-d21be0bd0e76423ba8928b78bb1b73f7
Source noteuspto-grants-1977_12