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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 461640Generated: October 29, 2026

Ethyl bromoacetate → Ethyl 4,5-dihydro-4-oxothiopyrano[3,2-b]indole-5-acetate

https://huagongshe.com/reaction/461640

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl bromoacetateHCID 7748—
ReactantThiopyrano[3,2-b]indol-4(5H)-oneHCID 20326608—
ProductEthyl 4,5-dihydro-4-oxothiopyrano[3,2-b]indole-5-acetateHCID 20326604—

Reaction Steps

By the same method as described in Example 7, 4.8 g of thiopyrano[3,2-b]indol-4(5H)-one is alkylated with ethyl bromoacetate to give 6.0 g of product, mp 163°-165° C, after recrystallization from ethyl acetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04064123
Source datasetuspto-grants-1977_12
ORD IDord-40fd097d08904239b6a1e38247841b49
Source noteuspto-grants-1977_12