Dopamine Hydrochloride → HCID 22800602, compound

HRID 461760Notes

Reaction equation

HRID 461760 reaction equation
[C:1]([NH:11][CH2:12][C:13]([NH:15][CH2:16][C:17]([N:19]1[CH2:26][CH2:25][CH2:24][C@H:20]1[C:21]([OH:23])=O)=[O:18])=[O:14])([O:3][CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:2].Cl.[NH2:28][CH2:29][CH2:30][C:31]1[CH:38]=[CH:37][C:35]([OH:36])=[C:33]([OH:34])[CH:32]=1>>[C:1]([NH:11][CH2:12][C:13]([NH:15][CH2:16][C:17]([N:19]1[CH2:26][CH2:25][CH2:24][C@H:20]1[C:21]([NH:28][CH2:29][CH2:30][C:31]1[CH:38]=[CH:37][C:35]([OH:36])=[C:33]([OH:34])[CH:32]=1)=[O:23])=[O:18])=[O:14])([O:3][CH2:4][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1)=[O:2]

Participants

3

Reactant 2

HCID 65340Dopamine HydrochlorideHCID 54489585HCID 54489585, compound

Product 1

HCID 22800602HCID 22800602, compound

Procedure

In the same manner as described in Example 1, 800 mg of carbobenzoxyglycylglycylproline and 380 mg of dopamine hydrochloride were reacted and treated to obtain N-carbobenzoxyglycylglycylprolyl dopamine. This compound was subjected to the catalytic reduction treatment in the same manner as described in Example 1. At the gel filtration, fractions Nos. 40 to 48 were collected. There was obtained 380 mg of a white powdery product, which was an acetate of the intended product. Elementary Analysis Values as C17H24N4O5.CH3COOH.1/2 H2O:

Workup

  1. customwere reacted
  2. additiontreated

Sources & evidence

ORD record
ord-17e739386a11435f844deb64627a505f
Source dataset
uspto-grants-1977_12
Patent number
US04064235

Reaction notes

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