Acetylalanylalanylleucine benzyl ester → Acetylalanylalanylleucine

Beteiligte Stoffe

Reaktionsschritte

Acetylalanylalanylleucine benzyl ester (2 mmole) is dissolved in denaturated ethyl alcohol (0.5 gal. benzene added to 100 gal. of absolute ethanol) (15 ml) and hydrogenated over 10% palladium/charcoal (0.1 gm) at 40 psi for 1/2 hour. The solution was filtered through Celite and evaporated in vacuo. The residue is triturated with diethyl ether to give crystalline acetylalanylalanylleucine, m.p. 185°-186°.

Herkunft & Nachweise