Dimethyl Sulfate → HCID 54506264, compound

HRID 461844Notes

Reaction equation

HRID 461844 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]1[NH:10][N:9]([CH3:11])[C:8](=[S:12])[S:7]1.S(OC)(O[CH3:17])(=O)=O.[K]>C(O)C>[CH:6](=[N:10][N:9]([CH3:11])[C:8]([S:7][CH3:17])=[S:12])[C:2]1[O:1][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 6497Dimethyl SulfateHCID 5462222PotassiumHCID 213928345-(Furan-2-yl)-3-methyl-1,3,4-thiadiazolidine-2-thione

Product 1

HCID 54506264HCID 54506264, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1 g of 2-(2-furyl)-4-methyl-1,3,4-thidiazolidine-5-thione was dissolved in 50 ml of warm ethanol, and after cooling to room temperature 1.26 g of dimethyl sulphate was added. After stirring for 2.5 hours at 50°, 0.69 g potassium was added, the mixture was heated for 1.5 hours at 50°, then allowed to stand overnight. The reaction mixture was filtered and the filtrate was evaporated to dryness. The residue was recrystallised from ethanol and pure S-methyl 3-furfurylidene- 2-methyl-dithiocarbazate (mp = 103°) was obtained.

Workup

  1. additionwas added
  2. temperaturethe mixture was heated for 1.5 hours at 50°
  3. waitto stand overnight
  4. filtrationThe reaction mixture was filtered
  5. customthe filtrate was evaporated to dryness
  6. customThe residue was recrystallised from ethanol

Sources & evidence

ORD record
ord-b87d8b3558254985bd1d8dcd23e21064
Source dataset
uspto-grants-1977_12
Patent number
US04064262

Reaction notes

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