HuagongsheHuagongshe Chemistry Print Report · For research reference only
2'-[2-(1-Methyl-2-piperidyl)ethyl]-4-nitrobenzanilide → 4-Amino-2'-[2-(1-methyl-2-piperidyl)-ethyl]benzanilide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2'-[2-(1-Methyl-2-piperidyl)ethyl]-4-nitrobenzanilide | HCID 20560086 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Amino-2'-[2-(1-methyl-2-piperidyl)-ethyl]benzanilide | HCID 20560018 | — |
Reaction Steps
Reduction of 2'-[2-(1-methyl-2-piperidyl)ethyl]-4-nitrobenzanilide (6.5 g., 0.018 mole) in 100 ml. of ethanol employing 2 g. of palladium on carbon catalyst (10%) according to Example 2 (a) affords 4-amino-2'-[2-(1-methyl-2-piperidyl)-ethyl]benzanilide. Crystallization of the product from acetonitrile provides the analytically pure substance, m.p. 147°-148.5° C. (corr.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04064254 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-859443eaecbc4a4fbcf624f50ce601b9 |
| Source note | uspto-grants-1977_12 |