HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Anisoyl chloride → 4-Methoxy-N-{2-[2-(1-methylpiperidin-2-yl)propyl]phenyl}benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Anisoyl chloride | HCID 7477 | — |
| Reactant | 2-[2-(1-Methylpiperidin-2-yl)propyl]aniline | HCID 20559949 | — |
| Product | 4-Methoxy-N-{2-[2-(1-methylpiperidin-2-yl)propyl]phenyl}benzamide | HCID 20560006 | — |
Reaction Steps
Reaction of 2-[2-(2-aminophenyl)-1-methylethyl]-1-methylpiperidine with anisoyl chloride, according to the procedure of Example 25, provides 4-methoxy-2'-[2-methyl-2-(1-methyl-2-piperidyl)ethyl]benzanilide as a 72:28 mixture of diastereoisomers (according to nmr), m.p. 125.5°-136.5° C. (corr.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04064254 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-1d311b2e98d2415db61afa15854b1f8b |
| Source note | uspto-grants-1977_12 |