HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-[2-(1-Ethylpiperidin-2-yl)ethyl]aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-{2-[2-(1-Ethylpiperidin-2-yl)ethyl]phenyl}formamide | HCID 20559971 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-[2-(1-Ethylpiperidin-2-yl)ethyl]aniline | HCID 20559983 | — |
Reaction Steps
A solution of 1-ethyl-2-(2-formamidophenethyl)piperidine (27.6 g., 0.11 mole), methanol (450 ml.) and concentrated HCl (100 ml.) allowed to stand for 24 hr. provides 2-(2-aminophenethyl)-1-ethylpiperidine, purified by distillation, yield 17.72 g. (69%), b.p. 107°-128° C./0.1 Torr, nD30° 1.5510.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04064254 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-f427d35201fa4899baf6b9f14bd54f23 |
| Source note | uspto-grants-1977_12 |