Hexane → HCID 21392667, compound

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Reaction Steps

0.01 Mole of exobicyclo[3.1.0]hex-2-yl acetaldehyde and 0.01 mole of sodium bisulfite are stirred in 20 ml. of water at room temperature until all of the aldehyde is dissolved. 0.02 Mole of sodium cyanide in 5 ml. of water is then added and the mixture stirred for 30 minutes at room temperature. The solution is then extracted three times with ethyl acetate and the combined ethyl acetate extract dried over anhydrous magnesium sulfate, filtered and then evaporated under vacuum to remove the solvent, yielding 1-(bicyclo[3.1.0]hex-2-yl)-3-cyano-3-hydroxypropane.

Provenance & Evidence