HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl formate → HCID 20317098, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl formate | HCID 8025 | — |
| Reactant | 2-Pyridone | HCID 8871 | — |
| Reactant | Methylamine hydrochloride | HCID 6364545 | — |
| Reactant | 3,5-Bis(3-chlorophenyl)-1-methylpyridin-4(1H)-one | HCID 12879264 | — |
| Reactant | 1,3-Bis(3-chlorophenyl)propan-2-one | HCID 23345739 | — |
| Product | HCID 20317098 | HCID 20317098 | — |
Reaction Steps
A 10 g. portion of 1,3-bis(3-chlorophenyl)-2-propanone was reacted with ethyl formate and methylamine hydrochloride to produce 7 g. of 3,5-bis(3-chlorophenyl)-1-methyl-4(1H)-pyridinone. A 6.4 g. portion of the pyridinone was reduced with 2 g. of lithium aluminum hydride and the products were separated by chromatography as described in the examples above. The yields were about 0.8 g. of Example 11, and 1.5 g. of Example 12. Example 11, m.p. 140°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04065290 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-587332f6b1c740be8ee1ef5827ace8a5 |
| Source note | uspto-grants-1977_12 |