Ethanol → HCID 54680399, compound

HRID 462061Notes

Reaction equation

HRID 462061 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([OH:13])=[CH:7][C:8](=[O:12])[NH:9]2)=[CH:4][CH:3]=1.[N+:14]([O-])([OH:16])=[O:15].C(O)C>C(O)(=O)C>[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([OH:13])=[C:7]([N+:14]([O-:16])=[O:15])[C:8](=[O:12])[NH:9]2)=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 944Nitric AcidHCID 54677681HCID 54677681, compound

Product 1

HCID 54680399HCID 54680399, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A suspension of 7-chloro-4-hydroxycarbostyril (0.5g.) in glacial acetic acid (4 ml.) was nitrated with concentrated nitric acid (0.7ml.) at 100° C and worked up in the usual manner to give the title compound, m.p. (aqueous ethanol) 166° - 167° C.

Sources & evidence

ORD record
ord-982507ccf33042f6a49752604054eec7
Source dataset
uspto-grants-1977_12
Patent number
US04065457

Reaction notes

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