HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → 1-[4-(Diethylamino)-2-butynyl]pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Dietylaminopropin | HCID 20010 | — |
| Reactant | Pyrrolidine | HCID 31268 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 1-[4-(Diethylamino)-2-butynyl]pyrrolidine | HCID 21390485 | — |
Reaction Steps
Following the procedure given in Example 1B, 7.8 g. (0.07 mole) of diethylpropargylamine, 3.8 g. of paraformaldehyde, 5.7 g. (0.08 mole) of pyrrolidine, and a trace of cuprous chloride in 80 ml. of dioxane was refluxed for 4 hours and allowed to stand overnight. After distillation and redistillation, the product, 1-[4-(diethylamino)-2-butynyl]pyrrolidine was obtained as a clear oil boiling at 68.0° C. at 0.05 mm.; ND25 = 1.4770.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04065471 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-923b6beafcf340ab9f38adcede1c9ede |
| Source note | uspto-grants-1977_12 |