Hydrochloric Acid → HCID 131710987, compound

Participants

Reaction Steps

0.5 g of the acetamido acid prepared in Example 10 was refluxed for 18 hours with 20 ml of 6N hydrochloric acid. The excess acid was removed in the rotary evaporator, leaving a semi-solid residue. This was dissolved in five ml of water and sodium bicarbonate solution added to pH 6-7, whereupon a voluminous white precipitate formed. After chilling for an hour, the solid was recovered by filtration and recrystallized from aqueous ethanol. The white crystals of the above-named product thus obtained melted at 222.5°-223° with decomposition.

Provenance & Evidence