Phthalic Anhydride → HCID 15643059, compound

HRID 462112Notes

Reaction equation

HRID 462112 reaction equation
[CH2:1]1[O:5][C:4]2[CH:6]=[C:7]([CH2:10][CH2:11][NH2:12])[CH:8]=[CH:9][C:3]=2[O:2]1.[C:13]1(=O)[O:18][C:16](=[O:17])[C:15]2=[CH:19][CH:20]=[CH:21][CH:22]=[C:14]12>C(O)(=O)C>[CH2:1]1[O:2][C:3]2[CH:9]=[CH:8][C:7]([CH2:10][CH2:11][N:12]3[C:16](=[O:17])[C:15]4=[CH:19][CH:20]=[CH:21][CH:22]=[C:14]4[C:13]3=[O:18])=[CH:6][C:4]=2[O:5]1

Participants

4

Reactant 2

HCID 6811Phthalic AnhydrideHCID 738741,3-Benzodioxole-5-ethanamine

Product 1

HCID 15643059HCID 15643059, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Forty-one g of 3,4,-methylenedioxyphenethylamine (0.25 moles) was refluxed with 36 g of phthalic anhydride (0.28 moles) and 65 ml. of acetic acid for 2.5 hours. The mixture was cooled whereupon it solidified. The solid mass was broken up and triturated with water and the solid recovered by filtration. Recrystallization from 300 ml of acetic acid and 125 ml of water gave white crystals of the above-named product, m.p. 139°-140.5°.

Workup

  1. temperatureThe mixture was cooled whereupon it
  2. customtriturated with water
  3. filtrationthe solid recovered by filtration
  4. customRecrystallization from 300 ml of acetic acid and 125 ml of water
  5. customgave white crystals of the above-named product, m.p. 139°-140.5°

Sources & evidence

ORD record
ord-33ee80bacf8c4558b38c1c65edd8a712
Source dataset
uspto-grants-1977_12
Patent number
US04065473

Reaction notes

Loading…