HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → Pyrrole-2-carboxaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Nicotyrine | HCID 10249 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Product | Pyrrole-2-carboxaldehyde | HCID 13854 | — |
| Product | 3-(1,5-Dimethyl-1H-pyrrol-2-yl)pyridine | HCID 53647270 | — |
Reaction Steps
The 1,5-dimethyl-2-(3-pyridyl) pyrrole is prepared from 1-methyl-2-(3-pyridyl) pyrrole by treatment with phosphorus oxychloride and dimethyl formamide to form a pyrrole-carboxaldehyde which is then subjected to a Wolff-Kishner reduction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04065561 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-1d01cb8088724a0e8ba8b62017a91214 |
| Source note | uspto-grants-1977_12 |