3-Amino-2,4,6-triiodobenzoic acid → 2,4,6-Triiodo-3-epsilon-aminocaproylaminobenzoic acid

HRID 462166Notes

Reaction equation

HRID 462166 reaction equation
[I:1][C:2]1[C:10]([NH2:11])=[C:9]([I:12])[CH:8]=[C:7]([I:13])[C:3]=1[C:4]([OH:6])=[O:5].C1(=O)[N:18]([CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][C:24](Cl)=[O:25])C(=O)C2=CC=CC=C12>>[I:1][C:2]1[C:10]([NH:11][C:24](=[O:25])[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][NH2:18])=[C:9]([I:12])[CH:8]=[C:7]([I:13])[C:3]=1[C:4]([OH:6])=[O:5]

Participants

3

Reactant 2

HCID 183873-Amino-2,4,6-triiodobenzoic acidHCID 594868N-(6-Chloro-6-oxohexyl)phthalimide

Product 1

HCID 203243482,4,6-Triiodo-3-epsilon-aminocaproylaminobenzoic acid

Procedure

The same procedure is used as for Compound I, using 2,4,6-triiodo-3-amino-benzoic acid as iodo starting material and ε-phthalimidocaproic acid chloride.

Sources & evidence

ORD record
ord-e7cdd99e255142c6979a18d36ef0fbcb
Source dataset
uspto-grants-1977_12
Patent number
US04065554

Reaction notes

Loading…