HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 21390694, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Thiophosgene | HCID 10040 | — |
| Reactant | 4-[3-(2-Furanyl)-1,2,4-oxadiazol-5-yl]benzenamine | HCID 23008201 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 21390694 | HCID 21390694 | 74.3% |
Reaction Steps
To a solution of 3-(2-furyl)-5-(4-aminophenyl)-1,2,4-oxadiazole (5.1 g, 0.02 mole) in 150 ml of dry tetrahydrofuran containing 3.1 ml of triethylamine, thiophosgene 2.53 g (0.02 mole) is added and the mixture is stirred at room temperature for 4 hours. After filtration, the solvent is evaporated in vacuo and the product is crystallized from petroleum ether to give 4.0 g (68%) of the title compound, m.p. 136°-137°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04065563 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-29459f1522874c0f8e1a9ae00da126f5 |
| Source note | uspto-grants-1977_12 |