Butyl chloroformate → HCID 21390884, compound

HRID 462182Notes

Reaction equation

HRID 462182 reaction equation
[CH2:1]([O:5][C:6](Cl)=[O:7])[CH2:2][CH2:3][CH3:4].[NH:9]([C:11]1[C:19]2[C:14](=[CH:15][C:16]([Cl:20])=[CH:17][CH:18]=2)[NH:13][N:12]=1)[NH2:10]>N1C=CC=CC=1>[CH2:1]([O:5][C:6]([NH:10][NH:9][C:11]1[C:19]2[C:14](=[CH:15][C:16]([Cl:20])=[CH:17][CH:18]=2)[NH:13][N:12]=1)=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 61140Butyl chloroformateHCID 21390872HCID 21390872, compound

Product 1

HCID 21390884HCID 21390884, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

0.04 mol of chlorocarbonic acid n-butyl ester is added dropwise at 0° - 5° C, while stirring, to 0.04 mol of 3-hydrazino-6-chloro-indazole in 20 ml of pyridine. The reaction mixture is stirred for 3 hours at room temperature and then poured into ice water, and the colorless crystals which have precipitated are isolated by filtration. 3-n-Butoxycarbonylhydrazino-6-chloroindazole is obtained. After recrystallisation from a mixture of ligroin and ethanol (9 : 1), the melting point is 150° - 152° C. (Yield, 78% of theory).

Workup

  1. customthe colorless crystals which have precipitated
  2. customare isolated by filtration

Sources & evidence

ORD record
ord-8dfc899d885346feaa3edd9db4a07570
Source dataset
uspto-grants-1977_12
Patent number
US04065568

Reaction notes

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