Methyl chloroformate → HCID 53848412, compound

HRID 462183Notes

Reaction equation

HRID 462183 reaction equation
[NH:1]([C:3]1[C:11]2[C:6](=[CH:7][C:8]([Cl:12])=[CH:9][CH:10]=2)[NH:5][N:4]=1)[NH2:2].[CH3:13][O:14][C:15](Cl)=[O:16]>N1C=CC=CC=1>[CH3:13][O:14][C:15]([NH:2][NH:1][C:3]1[C:11]2[C:6](=[CH:7][C:8]([Cl:12])=[CH:9][CH:10]=2)[NH:5][N:4]=1)=[O:16]

Participants

4

Reactant 2

HCID 6586Methyl chloroformateHCID 21390872HCID 21390872, compound

Product 1

HCID 53848412HCID 53848412, compoundYield 73%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Analogously to Example 1, 0.04 mol of 3-hydrazino-6-chloro-indazole and 0.044 mol of chlorocarbonic acid methyl ester in 25 ml of pyridine at 0° - 5° C, followed by 2 hours at room temperature, give 3-methoxycarbonylhydrazino-6-chloroindazole (melting point 223°- 224° C after recrystallisation from methanol: yield, 73% of theory).

Sources & evidence

ORD record
ord-1978c655d2d64e08886e4ea360acf239
Source dataset
uspto-grants-1977_12
Patent number
US04065568

Reaction notes

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