Isopropyl chloroformate → HCID 53938262, compound

HRID 462184Notes

Reaction equation

HRID 462184 reaction equation
[NH:1]([C:3]1[C:11]2[C:6](=[CH:7][C:8]([Cl:12])=[CH:9][CH:10]=2)[NH:5][N:4]=1)[NH2:2].[CH:13]([O:16][C:17](Cl)=[O:18])([CH3:15])[CH3:14]>N1C=CC=CC=1>[CH:13]([O:16][C:17]([NH:2][NH:1][C:3]1[C:11]2[C:6](=[CH:7][C:8]([Cl:12])=[CH:9][CH:10]=2)[NH:5][N:4]=1)=[O:18])([CH3:15])[CH3:14]

Participants

4

Reactant 2

HCID 7917Isopropyl chloroformateHCID 21390872HCID 21390872, compound

Product 1

HCID 53938262HCID 53938262, compoundYield 68%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Analogously to Example 1, 0.05 mol of 3-hydrazino-6-chloro-indazole and 0.05 mol of chlorocarbonic acid isopropyl ester in 30 ml of pyridine at 0° - 5° C, followed by 3 hours at room temperature, give 3-isopropoxycarbonylhydrazino-6-chloroindazole (melting point 184° - 185° C after recrystallisation from isopropanol: yield, 68% of theory).

Sources & evidence

ORD record
ord-e1795c30b98844daad1e98231649caf2
Source dataset
uspto-grants-1977_12
Patent number
US04065568

Reaction notes

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