HRID46219

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：OC1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1

HCID10940502

2,3,4,6-Tetrakis-O-(phenylmethyl)-D-glucopyranose

C34H36O6

2 次

结构：COc1c(CO[Si](C(C)C)(C(C)C)C(C)C)cc(Br)c2ccccc12

HCID67287764

未命名化合物

2 次

PRODUCTS

生成物

结构：COc1c(CO)cc([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)c2ccccc12

HCID67288992

未命名化合物

收率 85%

PROCEDURE

实验过程

With similar method described in Step 3 of Example 92, ((4-bromo-1-methoxynaphthalen-2-yl)methoxy)-triisopropylsilane (compound 68b, 21.3 g, 50.3 mmol) and 2,3,4,6-tetra-O-benzyl-D-glucopyranose (compound 2, 22.6 g, 41.9 mmol) were converted to title compound (25.3 g, 85%) as a white solid.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-786edd668bfc44639dcdb4dd7829a8f3
来源数据集: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08541380B2
来源说明: uspto-grants-2013_09

反应 SMILES

Br[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([O:12][CH3:13])=[C:4]([CH2:14][O:15][Si](C(C)C)(C(C)C)C(C)C)[CH:3]=1.[CH2:26]([O:33][C@@H:34]1[C@@H:40]([O:41][CH2:42][C:43]2[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=2)[C@H:39]([O:49][CH2:50][C:51]2[CH:56]=[CH:55][CH:54]=[CH:53][CH:52]=2)[C@@H:38]([CH2:57][O:58][CH2:59][C:60]2[CH:65]=[CH:64][CH:63]=[CH:62][CH:61]=2)[O:37][CH:35]1O)[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[CH3:13][O:12][C:5]1[C:6]2[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=2)[C:2]([C@H:35]2[C@H:34]([O:33][CH2:26][C:27]3[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=3)[C@@H:40]([O:41][CH2:42][C:43]3[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=3)[C@H:39]([O:49][CH2:50][C:51]3[CH:52]=[CH:53][CH:54]=[CH:55][CH:56]=3)[C@@H:38]([CH2:57][O:58][CH2:59][C:60]3[CH:61]=[CH:62][CH:63]=[CH:64][CH:65]=3)[O:37]2)=[CH:3][C:4]=1[CH2:14][OH:15]