Ethanolamine → HCID 3884686, compound

HRID 462195Notes

Reaction equation

HRID 462195 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH:6]=O.[NH:11]1[CH2:17][C:15](=[O:16])[NH:14][C:12]1=[O:13].C(CN)O>O>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH:6]=[C:17]1[NH:11][C:12](=[O:13])[NH:14][C:15]1=[O:16]

Participants

5

Reactant 3

HCID 700EthanolamineHCID 10006HydantoinHCID 115693-Methoxybenzaldehyde

Product 1

HCID 3884686HCID 3884686, compoundYield 79.9%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of m-methoxybenzaldehyde (2.00 g., 14.7 mmoles) and hydantoin (1.47 g.) in water (12 ml) was heated to 70°; monoethanolamine (1.35 g., 1.5 molar ratio) was then added and the mixture was heated in an oil bath at 90°-92° for 4 hours with magnetic stirring. Isolation in the usual manner gave the title compound as a beige solid (2.56 g.), m.p. 229°-231°.

Workup

  1. temperaturewas heated to 70°
  2. temperaturethe mixture was heated in an oil bath at 90°-92° for 4 hours with magnetic stirring

Sources & evidence

ORD record
ord-c443d6f1e0e24c4cae512236ab32bf76
Source dataset
uspto-grants-1977_12
Patent number
US04065570

Reaction notes

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