Acetic Acid → HCID 21390821, compound

Participants

Reaction Steps

The sample (0.1 g.) of 2-amino-5-[1-(2-hydroxyethyl)-5-nitro- 2-imidazolyl]thiadiazole is dissolved in 2 ml. of hot glacial acetic acid and a drop of concentrated sulfuric acid is added. The solution is refluxed for 45 minutes, cooled and poured on ice to give a yellow solid. This solid is collected, washed with water and dried; the yield is 0.1 g., melting point 159°-162° C. (turbid). A purified sample of the 2-amino-5-[1-(2-acetoxyethyl)- 5-nitro-2-imidazolyl]thiadiazole, melts at 164°-165.5° C.

Provenance & Evidence