HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Methylamino)ethanol → 2-{2-[N-(2-Hydroxyethyl)methylamino]-5-thiadiazolyl}-1-methyl-5-nitroimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Methylamino)ethanol | HCID 8016 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 2-(2-Piperidino-5-thiadiazolyl)-1-methyl-5-nitroimidazole | HCID 21390837 | — |
| Product | 2-{2-[N-(2-Hydroxyethyl)methylamino]-5-thiadiazolyl}-1-methyl-5-nitroimidazole | HCID 68118756 | — |
Reaction Steps
The preparation of the above compound is carried out essentially as described for the 2-piperidino derivative (Example 28), an equivalent of N-methylethanolamine replacing the piperidine. The pure compound melts at 158°-160° C. after recrystallization from methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04065567 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-da559262e11a4cd4991ae08c78971761 |
| Source note | uspto-grants-1977_12 |