HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexylamine → 2-(2-n-Octylamino-5-thiadiazolyl)-1-methyl-5-nitroimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexylamine | HCID 7965 | — |
| Reactant | Octylamine | HCID 8143 | — |
| Reactant | 2-(2-Cyclohexylamino-5-thiadiazolyl)-1-methyl-5nitroimidazole | HCID 21390861 | — |
| Product | 2-(2-n-Octylamino-5-thiadiazolyl)-1-methyl-5-nitroimidazole | HCID 68120260 | — |
Reaction Steps
The preparation of the above compound is carried out essentially as described for the 2-cyclohexylamino derivative (Example 38), an equivalent of n-octylamine replacing the cyclohexylamine. The crude product is purified by recrystallization from aqueous 2-methoxyethanol and then melts at 130°-132° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04065567 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-753b35837da44544a0a6e1d524189248 |
| Source note | uspto-grants-1977_12 |