HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → alpha-Sulfo-alpha-(p-nitrophenyl)acetic acid chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | alpha-Sulfo-alpha-(p-nitrophenyl)acetic acid | HCID 20449064 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | alpha-Sulfo-alpha-(p-nitrophenyl)acetic acid chloride | HCID 20556789 | 81.3% |
Reaction Steps
6.58 Grams (5.7 × 10-2M) of thionyl chloride, 2 ml. of ether and 2 drops of dimethylformamide were added to 1.5 g. (5.7 × 10-3M) of α-sulfo-α-(p-nitrophenyl)acetic acid to allow to react for 14.5 hours at room temperature. The reaction product was subjected to the evaporation to dryness under reduced pressure to obtain a crude desired product. Yield 81.3%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04065619 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-a35e28ba5d044c3bbf73d559348e2e04 |
| Source note | uspto-grants-1977_12 |