HCID 12595581, compound → HCID 12595610, compound

HRID 462297Notes

Reaction equation

HRID 462297 reaction equation
[CH2:1]1[O:23][C:4]2([CH2:9][CH2:8][C:7]([C:13]3[CH:18]=[CH:17][C:16]([C:19]([CH3:22])([CH3:21])[CH3:20])=[CH:15][CH:14]=3)([N:10]=[C:11]=O)[CH2:6][CH2:5]2)[O:3][CH2:2]1.ClC1C=CC(C2(N=C=O)CCC(=O)CC2)=CC=1>>[CH2:2]1[O:3][C:4]2([CH2:5][CH2:6][C:7]([C:13]3[CH:14]=[CH:15][C:16]([C:19]([CH3:21])([CH3:20])[CH3:22])=[CH:17][CH:18]=3)([NH:10][CH3:11])[CH2:8][CH2:9]2)[O:23][CH2:1]1

Participants

3

Reactant 2

HCID 12595581HCID 12595581, compoundHCID 20453342HCID 20453342, compound

Product 1

HCID 12595610HCID 12595610, compoundYield 94%

Procedure

Following the procedure of Example 1, Part G, but substituting an appropriate quantity of 4-(p-t-butylphenyl)-4-isocyanatocyclohexanone ethylene ketal for 4-p-chlorophenyl-4-isocyanatocyclohexanone there is obtained 4-(p-t-butylphenyl)-4-methylaminocyclohexanone ethylene ketal which as a m.p. 118.5°-121° C. (94% yield).

Sources & evidence

ORD record
ord-9762bb80c65d42eaa282f13baed0a934
Source dataset
uspto-grants-1977_12
Patent number
US04065573

Reaction notes

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