HRID46230

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：OC1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1

HCID10940502

2,3,4,6-Tetrakis-O-(phenylmethyl)-D-glucopyranose

C34H36O6

2 次

结构：COc1cc(Cl)c(CO[Si](C(C)C)(C(C)C)C(C)C)cc1Br

HCID53329406

未命名化合物

2 次

PRODUCTS

生成物

结构：COc1cc(Cl)c(CO)cc1C1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1

HCID53329585

未命名化合物

PROCEDURE

实验过程

With similar method described in Step 3 of Example 92, (5-bromo-2-chloro-4-methoxybenzyloxy)triisopropylsilane (compound 89, 27.2 g, 66.7 mmol) and 2,3,4,6-tetra-O-benzyl-D-glucopyranose (compound 2, 30.0 g, 55.6 mmol) were converted to title compound (22.6 g, 59%, ca. 8:1 mixture of anomers (13:0) as a white solid.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2c3a65c066ad4c4fa274a5b279ee8e5d
来源数据集: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08541380B2
来源说明: uspto-grants-2013_09

反应 SMILES

Br[C:2]1[C:3]([O:21][CH3:22])=[CH:4][C:5]([Cl:20])=[C:6]([CH:19]=1)[CH2:7][O:8][Si](C(C)C)(C(C)C)C(C)C.[CH2:23]([O:30][C@@H:31]1[C@@H:37]([O:38][CH2:39][C:40]2[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=2)[C@H:36]([O:46][CH2:47][C:48]2[CH:53]=[CH:52][CH:51]=[CH:50][CH:49]=2)[C@@H:35]([CH2:54][O:55][CH2:56][C:57]2[CH:62]=[CH:61][CH:60]=[CH:59][CH:58]=2)[O:34][CH:32]1O)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[Cl:20][C:5]1[CH:4]=[C:3]([O:21][CH3:22])[C:2]([CH:32]2[C@H:31]([O:30][CH2:23][C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=3)[C@@H:37]([O:38][CH2:39][C:40]3[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=3)[C@H:36]([O:46][CH2:47][C:48]3[CH:49]=[CH:50][CH:51]=[CH:52][CH:53]=3)[C@@H:35]([CH2:54][O:55][CH2:56][C:57]3[CH:58]=[CH:59][CH:60]=[CH:61][CH:62]=3)[O:34]2)=[CH:19][C:6]=1[CH2:7][OH:8]