HCID 131710998, compound → HCID 131711007, compound

HRID 462316Notes

Reaction equation

HRID 462316 reaction equation
C([O:5][C:6]([CH:8]([C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1)[C:9]([NH:11][CH:12]1[C:35](=[O:36])[N:14]2[C:15]([C:28]([O:30]C(C)(C)C)=[O:29])=[C:16]([CH:19]=[CH:20][C:21]([O:23]C(C)(C)C)=[O:22])[CH2:17][S:18][C@H:13]12)=[O:10])=[O:7])(C)(C)C.NC1C(=O)N2C(C(OC(C)(C)C)=O)=C(C=CC(OC(C)(C)C)=O)CS[C@H]12.CC1C=CC(S(O)(=O)=O)=CC=1>>[C:6]([CH:8]([C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1)[C:9]([NH:11][CH:12]1[C:35](=[O:36])[N:14]2[C:15]([C:28]([OH:30])=[O:29])=[C:16]([CH:19]=[CH:20][C:21]([OH:23])=[O:22])[CH2:17][S:18][C@H:13]12)=[O:10])([OH:7])=[O:5]

Participants

3

Reactant 2

HCID 131710998HCID 131710998, compoundHCID 131710999HCID 131710999, compound

Product 1

HCID 131711007HCID 131711007, compound

Procedure

In a manner similar to the procedure described in Example 21, the titled acid compound was prepared from tert-butyl 7-(2'-tert-butoxycarbonyl-2'-phenylacetamido)-3-(2'-tert-butoxycarbonylvinyl)-3-cephem-4-carboxylate, which ester was prepared by acylating tert-butyl 7-amino-3-(2'-tert-butoxycarbonylvinyl)-3-cephem-4-carboxylate-p-toluene sulfonate as described in Example 6.

Workup

  1. customwas prepared

Sources & evidence

ORD record
ord-ec94148bb5a3465dbe8d5f261f9ceac3
Source dataset
uspto-grants-1977_12
Patent number
US04065620

Reaction notes

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