Hydroxylamine, O-ethyl- → HCID 178449938, compound

HRID 462380Notes

Reaction equation

HRID 462380 reaction equation
[C:1]([CH:6]1[C:11](=[O:12])[CH:10]([CH3:13])[CH:9]([CH2:14][CH:15]([S:17]([CH2:19][CH3:20])=[O:18])[CH3:16])[CH2:8][C:7]1=[O:21])(=O)[CH2:2][CH2:3][CH3:4].[CH2:22]([O:24][NH2:25])[CH3:23]>C(O)C>[CH2:22]([O:24][NH:25][C:1](=[C:6]1[C:11](=[O:12])[CH:10]([CH3:13])[CH:9]([CH2:14][CH:15]([S:17]([CH2:19][CH3:20])=[O:18])[CH3:16])[CH2:8][C:7]1=[O:21])[CH2:2][CH2:3][CH3:4])[CH3:23]

Participants

4

Reactant 2

HCID 69357Hydroxylamine, O-ethyl-HCID 20398189HCID 20398189, compound

Product 1

HCID 178449938HCID 178449938, compoundYield 75.2%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
0 °C

Procedure

Into 20 ml of ethanol, 3.1 g of 2-butyryl-5-(2-ethylsulfinylpropyl)-4-methylcyclohexane-1,3-dione was dissolved and 0.61 g of ethoxyamine was dropped thereto at 0° C. and the resulting solution was stirred at room temperature for 3 hours. After completion of the reaction, the reaction solution was treated as in Example 1 to obtain 2.65 g of the desired compound as yellow oily material. Yield 74%, nD19 1.5348.

Workup

  1. customAfter completion of the reaction
  2. additionthe reaction solution was treated as in Example 1

Sources & evidence

ORD record
ord-90a98a29a3b64cde82199f180c838f66
Source dataset
uspto-grants-1985_05
Patent number
US04515729

Reaction notes

Loading…