Hydrazinecarboxylic acid, ethyl ester → HCID 13424595, compound

HRID 462406Notes

Reaction equation

HRID 462406 reaction equation
[C:1]([O:5]CC)(=O)[NH:2][NH2:3].Cl[C:9]1[N:10]=[N:11][C:12]([C:16]2[CH:21]=[CH:20][C:19]([C:22]#[N:23])=[CH:18][CH:17]=2)=[C:13]([CH3:15])[CH:14]=1>C(O)CCC>[CH3:15][C:13]1[C:12]([C:16]2[CH:21]=[CH:20][C:19]([C:22]#[N:23])=[CH:18][CH:17]=2)=[N:11][N:10]2[C:1](=[O:5])[NH:2][N:3]=[C:9]2[CH:14]=1

Participants

4

Reactant 2

HCID 20064Hydrazinecarboxylic acid, ethyl esterHCID 13424594HCID 13424594, compound

Product 1

HCID 13424595HCID 13424595, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

A 12.6 g. portion of ethyl carbazate is dissolved in 300 ml. of butanol. A 13.77 g. portion of 3-chloro-5-methyl-6-(p-cyanophenyl)pyridazine is added and the mixture is stirred at reflux for 18 hours. The mixture is cooled in ice and the solid is recovered by filtration and air dried, giving 6.3 g. of the desired product as a cream colored solid, m.p.>300° C.

Workup

  1. temperatureat reflux for 18 hours
  2. temperatureThe mixture is cooled in ice
  3. filtrationthe solid is recovered by filtration and air
  4. customdried
  5. customgiving 6.3 g

Sources & evidence

ORD record
ord-8a3c03f4af5e4ac38862210cbcca5a70
Source dataset
uspto-grants-1985_05
Patent number
US04515791

Reaction notes

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