Hydrazinecarboxylic acid, ethyl ester → HCID 13424596, compound

HRID 462407Notes

Reaction equation

HRID 462407 reaction equation
Cl[C:2]1[N:3]=[N:4][C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([N+:15]([O-:17])=[O:16])[CH:10]=2)=[C:6]([CH3:8])[CH:7]=1.[C:18](OCC)(=[O:21])[NH:19][NH2:20]>C(O)CCC>[CH3:8][C:6]1[C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([N+:15]([O-:17])=[O:16])[CH:10]=2)=[N:4][N:3]2[C:18](=[O:21])[NH:19][N:20]=[C:2]2[CH:7]=1

Participants

4

Reactant 2

HCID 20064Hydrazinecarboxylic acid, ethyl esterHCID 20398287HCID 20398287, compound

Product 1

HCID 13424596HCID 13424596, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

A mixture comprising 7.0 g. of 3-chloro-5-methyl-6-(m-nitrophenyl)-pyridazine (U.S. Pat. No. 4,092,311), 5.8 g. of ethyl carbazate and 60 ml. of butanol is refluxed for 18 hours, then cooled in an ice bath and filtered. The solid is air dried giving 2.96 g. of the desired product as a yellow solid, m.p.>300° C.

Workup

  1. temperaturecooled in an ice bath
  2. filtrationfiltered
  3. customdried
  4. customgiving 2.96 g

Sources & evidence

ORD record
ord-8862aefe17554695aaa19467ea0527c6
Source dataset
uspto-grants-1985_05
Patent number
US04515791

Reaction notes

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