反应详情

温度

105 °C

17 g of ethyl 2-methylene-4-phenylbutyrate (Example 1.4) and 3.6 g of ethylamine were dissolved in 50 ml of absolute ethanol and heated under 40 atmospheres of nitrogen at 105° C. for 20 hours. After the solvent had been removed, the residue was taken up in 5 normal hydrochloric acid, extracted with ether and the aqueous solution was adjusted to pH 9.5 with potassium carbonate, again extracted with ether, and this was dried with potassium carbonate and evaporated.

1. customAfter the solvent had been removed
2. extractionextracted with ether
3. extractionagain extracted with ether
4. dry with materialthis was dried with potassium carbonate
5. customevaporated