Epichlorohydrin → HCID 20398516, compound

HRID 462467Notes

Reaction equation

HRID 462467 reaction equation
[CH:1]1([O:7][CH2:8][CH2:9][C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[OH-].[Na+].[CH2:19]([CH:21]1[O:23][CH2:22]1)Cl>O>[CH:1]1([O:7][CH2:8][CH2:9][C:10]2[CH:11]=[CH:12][C:13]([O:16][CH2:19][CH:21]3[O:23][CH2:22]3)=[CH:14][CH:15]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 7835EpichlorohydrinHCID 14798Sodium HydroxideHCID 13187532HCID 13187532, compound

Product 1

HCID 20398516HCID 20398516, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

13.3 g (0.06 mol) of 4-(2-cyclohexyloxyethyl)-phenol, 3.04 (0.076 mol) of sodium hydroxide pellets and 50 cc of water are introduced into a round-bottomed flask. The mixture is stirred at ambient temperature and, when the solution has become homogeneous, 18.6 g (16 cc, 0.2 mol) of epichlorohydrin are introduced. The stirring is continued at ambient temperature for 16 hours. Extraction is carried out with diethyl ether and the organic phase is washed with water. It is dried over magnesium sulphate and the ether is driven off. This gives an oil, which is used directly in the next step.

Workup

  1. extractionExtraction
  2. washthe organic phase is washed with water
  3. dry with materialIt is dried over magnesium sulphate
  4. customThis gives an oil, which

Sources & evidence

ORD record
ord-56079e3662624cd6a11f316d7a176f86
Source dataset
uspto-grants-1985_05
Patent number
US04515814

Reaction notes

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