反应详情

It was found that the N-ethyl 4-(4-pyridinyl)isatoic anhydride prepared in the preceding examples cound be converted to 1-ethyl-1,4-dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic acid by (a) reacting it with the potassium salt of ethyl formyl acetate to form ethyl 1-ethyl-1,4-dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylate, and (b) hydrolyzing that ester.