HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Ethanedione, 1,2-bis(4-chlorophenyl)- → 4,5-Bis-(4-chlorophenyl)-5-hydroxy-2-thioxo-3-pyrroline-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Ethanedione, 1,2-bis(4-chlorophenyl)- | HCID 18946 | — |
| Reactant | 2-Cyanoethanethioamide | HCID 1416277 | — |
| Catalyst | Piperidine | HCID 8082 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4,5-Bis-(4-chlorophenyl)-5-hydroxy-2-thioxo-3-pyrroline-3-carbonitrile | HCID 13236225 | — |
Reaction Steps
A suspension of 22.3 g. 4,4'-dichlorobenzil, 6.5 g. 2-cyanothioacetamide, 20 drops of piperidine and 200 ml. chloroform is stirred for 20 hours at ambient temperature. The yellow precipitate obtained is filtered off with suction, well washed with chloroform and dried. There are obtained 22.0 g. of the desired compound in the form of yellow crystals; m.p. 213° C. (decomp.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04517185 |
| Source dataset | uspto-grants-1985_05 |
| ORD ID | ord-8d02aad0da4c4edcb6cbbdcdbe59e98d |
| Source note | uspto-grants-1985_05 |