HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 86740108, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | HCID 13235820 | HCID 13235820 | — |
| Reactant | HCID 54563280 | HCID 54563280 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86740108 | HCID 86740108 | 94% |
Reaction Steps
By the method described in Example 1 for the preparation of 2-(4-chlorophenyl)-2-bromomethyl-5-prop-1-yltetrahydrofuran, 2-methyl-5-(4-chlorophenyl)hept-5-en-2-ol (3.2 g), bromine (2.35 g), and pyridine (1.18 g) in dry dichloromethane (40 ml) gave 2-(4-chlorophenyl-2-(1-bromoethyl)-5,5-dimethyltetrahydrofuran (4.4 g, 94%), a mixture of diastereomers, as an orange oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04518415 |
| Source dataset | uspto-grants-1985_05 |
| ORD ID | ord-b94cafa679884a47921d723c6bf0249d |
| Source note | uspto-grants-1985_05 |