HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 463062Generated: October 26, 2026
Potassium Carbonate → 4-[(2-Oxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)oxy]butyl acetate
https://huagongshe.com/reaction/463062
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Butanol, 4-bromo-, 1-acetate | HCID 78491 | — |
| Reactant | 6-hydroxy-2,4-dihydro-1H-3,1-benzoxazin-2-one | HCID 13260484 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 4-[(2-Oxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)oxy]butyl acetate | HCID 13260494 | — |
Reaction Steps
One hundred two grams (0.62 mol) of 6-hydroxy-4H-3,1-benzoxazin-2-one are dissolved in 1 liter of dimethylsulfoxide and mixed with 227 gm (1.64 mol) of potassium carbonate and 166 gm (0.73 mol) of 4-acetoxy-butylbromide. The reaction mixture is stirred for six hours at 50° C., and then ice water is added. The precipitate is subjected to suction filtration, washed with water, and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04518597 |
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| Source dataset | uspto-grants-1985_05 |
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| ORD ID | ord-887f993626cf4a8e9077eccda071cc62 |
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| Source note | uspto-grants-1985_05 |
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