反应详情

One gram (0.0056 mol) of N-bromosuccinimide is gradually added to a solution of 2.13 gm (0.005 mol) of 6-[4-(3,4-dichlorophenylmercapto)-butoxy]-4,4-dimethyl-4H-3,1-benzoxazin-2-one in 50 ml of methanol, under stirring. After reaction for 24 hours, 500 ml of water at 80° C. is added, and the precipitate is subjected to suction filtration after stirring for two hours. By recrystallization from isopropanol/diisopropylether, crystals are obtained, melting point: 136°-139° C.

1. customAfter reaction for 24 hours
2. filtrationthe precipitate is subjected to suction filtration
3. stirringafter stirring for two hours
4. customBy recrystallization from isopropanol/diisopropylether, crystals
5. customare obtained