4'-Mercaptoacetanilide → 6-[4-(4-Acetamido-phenylmercapto)-butoxy]-4,4-dicyclohexyl-4H-3,1-benzoxazin-2-one

HRID 463105Notes

Reaction equation

HRID 463105 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:8]=[CH:9][C:10]2[NH:15][C:14](=[O:16])[O:13][C:12]([CH:23]3[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]3)([CH:17]3[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]3)[C:11]=2[CH:29]=1.[C:30]([NH:33][C:34]1[CH:39]=[CH:38][C:37]([SH:40])=[CH:36][CH:35]=1)(=[O:32])[CH3:31]>>[C:30]([NH:33][C:34]1[CH:39]=[CH:38][C:37]([S:40][CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]2[CH:8]=[CH:9][C:10]3[NH:15][C:14](=[O:16])[O:13][C:12]([CH:23]4[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]4)([CH:17]4[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]4)[C:11]=3[CH:29]=2)=[CH:36][CH:35]=1)(=[O:32])[CH3:31]

Participants

3

Reactant 2

HCID 707774'-MercaptoacetanilideHCID 132604996-(4-chlorobutoxy)-4,4-dicyclohexyl-4H-3,1-benzoxazin-2-one

Product 1

HCID 132605376-[4-(4-Acetamido-phenylmercapto)-butoxy]-4,4-dicyclohexyl-4H-3,1-benzoxazin-2-one

Procedure

Prepared analogously to Example 1 from 6-(4-chlorobutoxy)-4,4-dicyclohexyl-4H-3,1-benzoxazin-2-one and 4-acetamido-thiophenol.

Sources & evidence

ORD record
ord-e969125799e84905a82a780885a8dc5f
Source dataset
uspto-grants-1985_05
Patent number
US04518597

Reaction notes

Loading…