6-hydroxy-2,4-dihydro-1H-3,1-benzoxazin-2-one → 6-[4-(4-chloro-phenylmercapto)-butoxy]-4H-3,1-benzoxazin-2-one

HRID 463147Notes

Reaction equation

HRID 463147 reaction equation
[OH:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:10][C:9](=[O:11])[O:8][CH2:7][C:6]=2[CH:12]=1.[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([S:20][CH2:21][CH2:22][CH2:23][CH2:24]Cl)=[CH:16][CH:15]=1>>[Cl:13][C:14]1[CH:15]=[CH:16][C:17]([S:20][CH2:21][CH2:22][CH2:23][CH2:24][O:1][C:2]2[CH:3]=[CH:4][C:5]3[NH:10][C:9](=[O:11])[O:8][CH2:7][C:6]=3[CH:12]=2)=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 132604846-hydroxy-2,4-dihydro-1H-3,1-benzoxazin-2-oneHCID 540931394-(4-Chlorophenylmercapto)-butylchloride

Product 1

HCID 132605506-[4-(4-chloro-phenylmercapto)-butoxy]-4H-3,1-benzoxazin-2-one

Procedure

Prepared analogously to Example 5 from 6-hydroxy-4H-3,1-benzoxazin-2-one and 4-(4-chloro-phenylmercapto)-butylchloride (prepared from 4-(4-chloro-phenylmercapto)-butanol and thionyl chloride).

Sources & evidence

ORD record
ord-cdc2230f118740a38920963aba6fc19e
Source dataset
uspto-grants-1985_05
Patent number
US04518597

Reaction notes

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