4'-Mercaptoacetanilide → 7-[4-(4-Acetamido-phenylmercapto)-butoxy]-4,4-dimethyl-4H-3,1-benzoxazin-2-one

HRID 463192Notes

Reaction equation

CS(O[CH2:6][CH2:7][CH2:8][CH2:9][O:10][C:11]1[CH:23]=[CH:22][C:14]2[C:15]([CH3:21])([CH3:20])[O:16][C:17](=[O:19])[NH:18][C:13]=2[CH:12]=1)(=O)=O.[C:24]([NH:27][C:28]1[CH:33]=[CH:32][C:31]([SH:34])=[CH:30][CH:29]=1)(=[O:26])[CH3:25]>>[C:24]([NH:27][C:28]1[CH:33]=[CH:32][C:31]([S:34][CH2:6][CH2:7][CH2:8][CH2:9][O:10][C:11]2[CH:23]=[CH:22][C:14]3[C:15]([CH3:20])([CH3:21])[O:16][C:17](=[O:19])[NH:18][C:13]=3[CH:12]=2)=[CH:30][CH:29]=1)(=[O:26])[CH3:25]

Participants

Reactant 2

HCID 707774'-Mercaptoacetanilide

HCID 20281668HCID 20281668, compound

Product 1

HCID 202816727-[4-(4-Acetamido-phenylmercapto)-butoxy]-4,4-dimethyl-4H-3,1-benzoxazin-2-one

Procedure

Prepared analogously to Example 210 from 7-(4-methanesulfonyloxy-butoxy)-4,4-dimethyl-4H-3,1-benzoxazin-2-one and 4-acetamido-thiophenol.

Sources & evidence

ORD record: ord-14accbbb2ed6459488622d04a0d4d684
Source dataset: uspto-grants-1985_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04518597

Reaction notes

Loading…